The Hawthorns and the Select of Lythari

A group of hunters established by the Continuum in the Third Age, the Hawthorns are Druids who dedicate themselves to the eradication of undead, and especially vampires. 

At the start of the Fourth Age a dissenting group of Hierophants broke off from the Continuum and established the Aeternium. It sought to create a group of vampire killers from elves who were taught how to shapeshift. The Select of Lythari was born, but their gift of shapechanging went terribly wrong when some of the Select had an adverse reaction to consuming vampire blood. They went feral and became known as therianthropes... able to reproduce and create more of their kind, but also able to attack and infect others with therianthropy.

Therianthropes have been reported who are werewolves, weretigers, wereswine, werespiders, weresharks, wererays, wereravens, wererats, werepanthers, werelions, wereleopards, werejaguars, werejackals, werehyenas, werefox, werecrocodiles, wereboars, werebears, werebats, werebadgers, and others.